Enterotypes

George Paschalidis has been researching and discussing the connection between the brain and the gut, since 2002. Both systems activate common neurological, hormonal and immunological functions and he referred to the intestine and the bacterial flora as “the second brain”.

A research of the European Molecular Biology Laboratory (EMBL) on human intestinal flora was published in May 2011. According to the research, the gastrointestinal tract is different in every person, but the number and type of bacteria inhabiting it is categorised only in three perfectly distinct groups of bacteria, which they call enterotypes. Each of the three enterotypes is related to the level variations of one of the three genera of intestinal bacteria. Bacteroids, Prevotella and Ruminococcus. These can now be classified into only three distinct groups, the enterotypes:

• Enterotype 1 with higher levels of Bacteroids
• Enterotype 2 with higher levels of Prevotella
• Enterotype 2 with higher levels of Ruminococcus

There is an absolute identification of the three Bacteria communities in the human gastrointestinal system with the three Types of human in the Tri-Anthropo-Type Paschalidis Model. Specifically, A Type corresponds to enterotype 1, B Type to enterotype 2, and C Type to enterotype 3.

The two brains are almost identical; they consist of the same cells, the same principles of operation and the same receptors. They continuously influence each other. It is important that both of these brains function optimally. The intestinal type, the brain-intestine connection and the increase of the Total Hormonal Disruption affect the assimilation of biometals that are essential for the function of the synapses. The understanding of the neuronal synapses functioning and the determination of the Total Hormonal Disruption Index can contribute to disease prevention.

Recent scientific research findings indicate that there is a correlation between biometal assimilation and enterotype of each human Type. Alterations in the concentration of neurotransmitters and biometals after stress lead to the manifestation of physical and mental disorders. This corresponds to an increase in the Total Hormone Disorder index.